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Min J, Zhang X, Cheng X, Grewal SI, Xu RM: Construction of the SET area histone lysine methyltransferase Clr4. In each proteins, the walls of the lysine-binding channel are fashioned by hydrophobic residues that have interaction in van der Waals interactions with the lysine facet chain (Figure 4b,c ). At the base of the channel is the methyltransfer pore, which connects the pocket to the AdoMet-binding cleft.
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